000			02149nam a2200241 4500
999			_c14199 _d14199
082			_aRef 373.07 N2196 2026
245			_aNature to nurture : _ba chitosan-based peel-and-stick heat patch for menstrual plan / _cby Nicole Abigail F. Alejo, Simeon IV B. Barranco, Raizah Jerielle C. Betita, Kissnher Martin T. Gabales, and Hariete Jean S. Gonzales.
260			_a[Iloilo City] : _b[Ateneo de Iloilo], _cc2026.
300			_a46 p.
520			_aChitosan, a biodegradable and biocompatible polysaccharide derived from giant tiger prawn (Penaeus monodon) shells, was investigated in this quantitative true experimental study to address the gap in accessible and eco-friendly menstrual pain relief solutions amid period poverty in marginalized Philippine communities, wherein chitosan was extracted through systematic demineralization with hydrochloric acid, deproteinization with sodium hydroxide, and deacetylation processes before being formulated with polyvinyl alcohol (PVA), glycerol, and a cornstarch-xanthan gum heat-retention layer into 100%, 75%, and 50% heat patches, which were evaluated under controlled laboratory conditions using a protein denaturation test to measure anti-inflammatory activity and thermal stability testing through mass loss computation with data analyzed using descriptive statistics, one-way ANOVA, and Tukey post hoc comparisons, revealing that chitosan concentration significantly affected performance as the 100% formulation demonstrated the highest protein denaturation inhibition, and lowest mass loss, leading to the conclusion that increasing chitosan concentration enhanced patch effectiveness and demonstrated strong potential as a sustainable, cost-effective material for menstrual pain relief.
526			_a300-399
650			_aChitosan.
650			_aDysmenorrhea.
650			_aHeat therapy.
650			_aBiomedical materials.
650			_aDrug delivery systems.
700			_aAlejo, Nicole Abigail F.
700			_aBarranco, Simeon IV B.
700			_aBetita, Raizah Jerielle C.
700			_aGabales, Kissnher Martin T.
700			_aGonzales, Hariete Jean S.
942			_2ddc _cBK