000			02641nam a2200253 4500
999			_c14198 _d14198
082			_aRef 373.07 V834 2026
245			_aIn vitro assessment of the antibacterial properties of santan flower (Ixora coccinea) ethanolic extract against group A streptococcus : _ba potential component in treating strep throat / _cby Lanze Daniel M. Tabanda, Charinna Carmel D. Nolasco, Luke Anthony S. Bautista, John Cyrus G. Dividina, and Queency Grace S. Tres Reyes.
260			_a[Iloilo City] : _b[Ateneo de Iloilo], _cc2026.
300			_a39 p.
520			_aIn the past years, as medicines began to be more accessible to everyone, antimicrobial resistance has occurred due to human misuse and overuse. This study explored the anti-bacterial properties of Santan (Ixora coccinea) flower against the bacterium Group A Streptococcus. The Kirby-Bauer method was used to identify the potential properties of Ixora coccinea Flower ethanolic extract as a potential component to inhibit the bacterium GAS. This organism was exposed to different concentrations of the ethanolic extract of Ixora coccinea flower, the positive control, penicillin G (Benzylpenicillin), and the negative control, distilled water, showed a significant difference in the mean of the zone of inhibition. It was observed that the findings show from the varying concentration of Ixora coccinea (50%, 75%, 100%) that the W-value yielded ±3.83 and the p-value yielded 0.167, which does not reach statistical significance (p<0.05). In conclusion, the study shows that the tested concentrations were not able to yield any zone of inhibition or inhibit the bacteria. The researchers recommend future experiments to explore different extraction methods of the Ixora coccinea flowers, such as methanol, hydroalcoholic, and aqueous extraction, to use Dimethyl Sulfoxide (DMSO) instead of distilled water for the diluent, to include more replicates and wider range of concentrations, to conduct a phytochemical analysis of Ixora coccinea to identify the specific bioactive compounds that are present and to use the leaves instead of flowers, which may inhibit the Group A Streptococcus and yield a zone of inhibition results.
526			_a300-399
650			_aIxora coccinea.
650			_aStreptococcus pyogenes.
650			_aAntibacterial agents.
650			_aPlant extracts.
650			_aMedicinal plants.
650			_aIn vitro techniques.
700			_aTabanda, Lanze Daniel M.
700			_aNolasco, Charinna Carmel D.
700			_aBautista, Luke Anthony S.
700			_aDividina, John Cyrus G.
700			_aTres Reyes, Queency Grace S.
942			_2ddc _cBK