02588nam a2200229   4500082002500000245033100025260004900356300001000405520163000415526001202045650002002057650002802077650002602105650002002131650002202151650002502173700003002198700003402228700003202262700003002294700003402324  aRef 373.07 V834 2026  aIn vitro assessment of the antibacterial properties of santan flower (Ixora coccinea) ethanolic extract against group A streptococcus  :ba potential component in treating strep throat /cby Lanze Daniel M. Tabanda, Charinna Carmel D. Nolasco, Luke Anthony S. Bautista, John Cyrus G. Dividina, and Queency Grace S. Tres Reyes.  a[Iloilo City] :b[Ateneo de Iloilo],cc2026.  a39 p.  aIn the past years, as medicines began to be more accessible to everyone, antimicrobial resistance has occurred due to human misuse and overuse. This study explored the anti-bacterial properties of Santan (Ixora coccinea) flower against the bacterium Group A Streptococcus. The Kirby-Bauer method was used to identify the potential properties of Ixora coccinea Flower ethanolic extract as a potential component to inhibit the bacterium GAS. This organism was exposed to different concentrations of the ethanolic extract of Ixora coccinea flower, the positive control, penicillin G (Benzylpenicillin), and the negative control, distilled water, showed a significant difference in the mean of the zone of inhibition. It was observed that the findings show from the varying concentration of Ixora coccinea (50%, 75%, 100%) that the W-value yielded ±3.83 and the p-value yielded 0.167, which does not reach statistical significance (p<0.05). In conclusion, the study shows that the tested concentrations were not able to yield any zone of inhibition or inhibit the bacteria. The researchers recommend future experiments to explore different extraction methods of the Ixora coccinea flowers, such as methanol, hydroalcoholic, and aqueous extraction, to use Dimethyl Sulfoxide (DMSO) instead of distilled water for the diluent, to include more replicates and wider range of concentrations, to conduct a phytochemical analysis of Ixora coccinea to identify the specific bioactive compounds that are present and to use the leaves instead of flowers, which may inhibit the Group A Streptococcus and yield a zone of inhibition results.  a300-399  aIxora coccinea.  aStreptococcus pyogenes.  aAntibacterial agents.  aPlant extracts.  aMedicinal plants.  aIn vitro techniques.  aTabanda, Lanze Daniel M.   aNolasco,  Charinna Carmel D.   aBautista,  Luke Anthony S.   aDividina,  John Cyrus G.   aTres Reyes, Queency Grace S.