| 000 -LEADER |
|---|
| fixed length control field |
02617nam a2200253 4500 |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
Ref 373.07 P5699 2026 |
| 245 ## - TITLE STATEMENT |
|---|
| Title |
Phytochemical screening and hypoglycemic evaluation of red button ginger (Costud woodsonii) leaf extract using alpha-amylase inhibitory assay / |
| Statement of responsibility, etc. |
by Venice Xandria L. Abella, Risa S. Alimonsurin, Ken S. Cabanalan, Jerco Andrei D. Gutierrez, and Nicole Francesca T. Quiblatin. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
|---|
| Place of publication, distribution, etc. |
[Iloilo City] : |
| Name of publisher, distributor, etc. |
[Ateneo de Iloilo], |
| Date of publication, distribution, etc. |
c2026. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent/Page number |
55 p. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
The increasing prevalence of diabetes mellitus, a chronic metabolic disorder affecting a large portion of the global population, highlights the urgent need to explore alternative and complementary biological treatments. Red button ginger (Costus woodsonii), traditionally used in herbal medicine, is known to contain bioactive phytoconstituents with potential antidiabetic properties. This study investigated the chemical composition and a-amylase inhibitory activity of red button ginger leaf extract as a potential natural antidiabetic agent. Qualitative phytochemical screening of the leaf extract confirmed the presence of several bioactive compounds, including flavonoids, saponins, tannins, carbohydrates, proteins, and amino acids. The a-amylase inhibitory assay was conducted using male and female saliva samples, with acarbose serving as the positive control. In the male saliva group, acarbose exhibited a high inhibition rate of 72.99%, while red button ginger extract demonstrated dose-dependent inhibition of 11.39%, 23.21%, and 36.71% at low, medium, and high concentrations, respectively. Similarly, in the female saliva group, acarbose showed 73.28% inhibition, whereas the extract produced inhibitory effects of 12.07%, 23.71%, and 37.50% across increasing concentrations. The results indicate that red button ginger leaf extract possesses significant a-amylase inhibitory activity in a concentration-dependent manner, supporting its traditional use and suggesting its potential as a natural antidiabetic agent. Further studies are recommended to isolate specific active compounds and evaluate their mechanisms of action. |
| 526 ## - STUDY PROGRAM INFORMATION NOTE |
|---|
| PROGRAM TYPE |
Social Sciences (how people live and work in society; law, government and institutions) |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Costus woodsonii. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Plant Extracts. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Hypoglycemic Agents. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Alpha-Amylase Inhibitors. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Phytochemicals. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Diabetes Mellitus – Alternative Treatment. |
| 700 ## - ADDED ENTRY--PERSONAL NAME/OTHER AUTHORS |
|---|
| Personal name |
Abella, Venice Xandria L. |
| 700 ## - ADDED ENTRY--PERSONAL NAME/OTHER AUTHORS |
|---|
| Personal name |
Alimonsurin, Risa S. |
| 700 ## - ADDED ENTRY--PERSONAL NAME/OTHER AUTHORS |
|---|
| Personal name |
Cabanalan, Ken S. |
| 700 ## - ADDED ENTRY--PERSONAL NAME/OTHER AUTHORS |
|---|
| Personal name |
Gutierrez, Jerco Andrei D. |
| 700 ## - ADDED ENTRY--PERSONAL NAME/OTHER AUTHORS |
|---|
| Personal name |
Quiblatin, Nicole Francesca T. |
| 942 ## - ADDED ENTRY ELEMENTS |
|---|
| Classification |
|
| Item type |
Book |
